Characterization of 35 new cases with four different MPLW515 mutations and essential thrombocytosis or primary myelofibrosis
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چکیده
منابع مشابه
Characterization of 35 new cases with four different MPLW515 mutations and essential thrombocytosis or primary myelofibrosis.
MLL Munich Leukemia Laboratory, Munich; Clinic for Stem Cell Transplantation, University Hospital of Hamburg, Hamburg-Eppendorf; University Hospital of Essen, Department of Bone Marrow Transplantation, Essen; Munich Oncology Practice, MVZ Elisenhof, Munich; Hematology & Oncology Practice, Plüderhausen; Hematology & Oncology Group Practice, Regensburg; Medical Treatment Centre Osthessen Ltd., He...
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Comparison of the Mutational Profiles of Primary Myelofibrosis, Polycythemia Vera, and Essential Thrombocytosis
Objectives To compare the mutational profiles of patients with primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocytosis (ET). Methods Next-generation sequencing results of 75 cases of PMF, 33 cases of PV, and 27 cases of ET were compared. Results Mutation rates of ASXL1 and SRSF2 were significantly higher in PMF than in PV or ET. ASXL1 mutations appeared to be more ...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2009
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.13224